Latest Posts
News, insights, and updates from RootPath.
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How do we ensure all MHCs of interest are expressed?
In cell-based assays of TCR:pMHC recognition, such as our TCR Decoder™ service, it is critical that all functional candidate MHC molecules are expressed. This is easier said than done. Here’s how we ensure this through an elaborate scheme, how biology and common reagents throw curve balls at us, and how we overcome the challenges.
Read more → -
How we ensure antigen expression
In cell-based assays of TCR:pMHC recognition, such as our TCR Decoder™ service, it is critical that all functional candidate MHC molecules are expressed. This is easier said than done. Here’s how we ensure this through an elaborate scheme, how biology and common reagents throw curve balls at us, and how we overcome the challenges.
Read more →